Ampicillin in breast milk during puerperal infections.

Abstract

Low concentrations of ampicillin were found in colostrum/breast milk from 6 mothers treated with pivampicillin 1.05 to 2.1 g daily during the first to eighth day postpartum in the maternity ward. It was calculated that the breast-fed infant could theoretically receive 0.05-0.37% of the dose/kg given to the mother. It is concluded that direct exposure of the breast-fed infant suckling from a mother under treatment with ampicillin or pivampicillin seems to be minimal.

• Authors: I Matheson, M Samseth, H A Sande
• Journal: European journal of clinical pharmacology (Eur J Clin Pharmacol) Vol. 34 Issue 6 Pg. 657-9 ( 1988) ISSN: 0031-6970 [Print] Germany
• PMID: 3169119 (Publication Type: Journal Article)

Chemical References

• Pivampicillin
• Ampicillin

Topics

• Ampicillin (analogs & derivatives, analysis)
• Female
• Humans
• Milk, Human (analysis)
• Pivampicillin (metabolism, therapeutic use)
• Pregnancy
• Puerperal Infection (drug therapy, metabolism)