Abstract | OBJECTIVES: METHODS: RESULTS: The 3 subjects in this series demonstrated clinical improvement on ketogenic diet. Two subjects showed reversal of some brain lesions on repeat MRI following initiation of ketogenic diet. Of the 21 published cases with serial MRIs, 13 patients underwent some form of treatment, and of this smaller subset 4 patients had repeat MRIs that showed definitive improvement. In both our described cases and those published in the literature, improvement occurred in lesions in the basal ganglia. CONCLUSIONS:
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Authors | Emily Shelkowitz, Can Ficicioglu, Nicholas Stence, Johan Van Hove, Austin Larson |
Journal | Journal of child neurology
(J Child Neurol)
Vol. 35
Issue 2
Pg. 137-145
(02 2020)
ISSN: 1708-8283 [Electronic] United States |
PMID | 31665995
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adolescent
- Child, Preschool
- Diet, Ketogenic
(methods)
- Female
- Gray Matter
(diagnostic imaging, physiopathology)
- Humans
- Magnetic Resonance Imaging
(methods)
- Male
- Pyruvate Dehydrogenase Complex Deficiency Disease
(diet therapy)
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