The efficacy of Tadalafil 5mg in the treatment of lower urinary tract symptoms in patients where alpha blocker treatments have failed in terms of lower urinary tract symptoms.

Abstract

OBJECTIVES:

To investigate the efficacy of tadalafil 5mg in patients with lower urinary tract symptoms who failed alpha blocker treatment.

PATIENTS AND METHODS:

Twenty-three patients were included. Patient consent was obtained after explaining the efficacy of tadalafil 5mg in lower urinary tract symptoms. Before initiating tadalafil 5mg treatment, prostate cancer and urinary tract infection in the patients were eliminated. IPSS, IIEF-5 and Qmax values were assessed before and one month after tadalafil 5mg treatment. Difference between two assessments was evaluated by the Wilcoxon method.

RESULTS:

After 1 month of Tadalafil 5mg treatment, IPSS decreased and IIEF-5 and Qmax increased. The difference between two assessments were statistically significant.

CONCLUSION:

Tadalafil 5mg once daily in the treatment of BPH/LUTS is found to be successful in patients who failed previous alpha blocker treatment.

• Authors: Ali Atan, Fazlı Polat, Süleyman Yeşil, Ali Ünsal, Ender Cem Bulut, Haluk Tokuçoğlu, Ahmet Emin Doğan
• Journal: Archivos espanoles de urologia (Arch Esp Urol) Vol. 72 Issue 7 Pg. 670-676 (Sep 2019) ISSN: 0004-0614 [Print] Spain
• Vernacular Title: Eficacia de Tadalafilo 5 mg en el tratamiento de los síntomas del tracto urinario inferior en pacientes tras fallo de los alfabloqueantes.
• PMID: 31475678 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Phosphodiesterase 5 Inhibitors
• Tadalafil

Topics

• Erectile Dysfunction
• Humans
• Lower Urinary Tract Symptoms (drug therapy)
• Male
• Phosphodiesterase 5 Inhibitors (therapeutic use)
• Prostatic Hyperplasia
• Tadalafil (therapeutic use)
• Treatment Outcome