Cribriform-morular variant of papillary thyroid carcinoma and its association with familial adenomatous polyposis.

Abstract

The cribriform-morular variant of papillary thyroid carcinoma (CMV-PTC) is an uncommon variant of papillary thyroid carcinoma. CMV-PTC can be associated with familial adenomatous polyposis (FAP), an autosomal-dominant polyposis syndrome caused by a mutation in the APC gene that leads to a disruption of the Wnt/beta-catenin pathway. Understanding the relation between CMV-PTC and FAP is a diagnostic tool for both pathologists and clinicians, because FAP has several implications for patients and their families.

• Authors: Alejandro Perez, Sarah Findeis, Atin Agarwal, Julia Berry, Katie King
• Journal: Proceedings (Baylor University. Medical Center) (Proc (Bayl Univ Med Cent)) Vol. 32 Issue 3 Pg. 399-401 (Jul 2019) ISSN: 0899-8280 [Print] United States
• PMID: 31384200 (Publication Type: Case Reports)