Multiple tuberous and tendinous xanthomas diagnosed on fine-needle aspiration cytology-report of a rare case.

Abstract

Xanthomas are papulonodular skin lesions present in lipoprotein metabolism disorders, which result in cholesterol deposits in subcutaneous tissue, tendons, ligaments, periosteum, etc. A 11-year-old male presented with multiple soft tissue swellings, prominently over joints. Fine-needle aspiration (FNA) from multiple sites had similar appearance with foamy histocytes and giant cells. Oil Red O and polarized microscopy were also positive for fat. We describe an unusual case of tendinous and tuberous xanthoma diagnosed by cytology. Acquaintance with fine-needle aspiration cytology findings in xanthomas can help to avoid the need of surgical biopsy, as xanthomas can regress on medical therapy alone.

• Authors: Santosh Tummidi, Kanchan Kothari, Amey Rojekar, Ashish Tiwari
• Journal: Diagnostic cytopathology (Diagn Cytopathol) Vol. 47 Issue 9 Pg. 939-942 (Sep 2019) ISSN: 1097-0339 [Electronic] United States
• PMID: 31169968 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2019 Wiley Periodicals, Inc.

Topics

• Biopsy, Fine-Needle
• Child
• Humans
• Male
• Skin Neoplasms (diagnosis, metabolism, pathology)
• Xanthomatosis (diagnosis, metabolism, pathology)