Pfeifer-Weber-Christian disease and successful treatment with mycophenolate mofetil: a case report.

Abstract

Inflammatory conditions manifest with a broad spectrum of signs and symptoms. Panniculitis is such a condition affecting the subcutaneous fat and presents as tender erythematous nodules. It is also associated with a systemic response and has been described in the literature as early as in 1892 by Pfeifer and in the 1920s by Weber and Christian. We present an unusual case of a Caucasian man with recurrent febrile illness, systemic inflammatory response and renal dysfunction requiring acute high dependency care. The authors successfully treated him with an antiproliferative agent, mycophenolate mofetil, which resulted in preventing him from having further episodes.

• Authors: Subash Somalanka, Ini Udo, Hari Nair, Shashidhar Baikunje
• Journal: BMJ case reports (BMJ Case Rep) Vol. 12 Issue 5 (May 22 2019) ISSN: 1757-790X [Electronic] England
• PMID: 31122958 (Publication Type: Case Reports, Journal Article)
• Copyright: © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Chemical References

• Immunosuppressive Agents
• Mycophenolic Acid

Topics

• Aged
• Diagnosis, Differential
• Fever (etiology)
• Humans
• Immunosuppressive Agents (administration & dosage, therapeutic use)
• Male
• Mycophenolic Acid (administration & dosage, therapeutic use)
• Panniculitis, Nodular Nonsuppurative (complications, diagnosis, drug therapy)
• Syndrome