Steroid-resistant eosinophilic fasciitis successfully treated with addition of extracorporeal photopheresis.

Abstract

Eosinophilic fasciitis (EF) is an uncommon fibrosing disease of the fascia with characteristic cutaneous and hematologic manifestations. Although EF is most commonly treated with corticosteroids at the beginning, a considerable number of patients show an inadequate response and hence various therapeutic strategies have been tried, including extracorporeal photopheresis (ECP). We describe the case of a 66-year-old woman with steroid-resistant EF that improved significantly after ECP was added to her treatment regimen. To date, only six cases of this therapeutic strategy have been reported in English literature.

• Authors: Felipe Partarrieu-Mejías, María Macarena Giacaman-Von der Weth, Amparo Pérez-Ferriols, Rosa Goterris-Viciedo, Victor Alegre-de Miquel
• Journal: Dermatologic therapy (Dermatol Ther) Vol. 32 Issue 4 Pg. e12926 (07 2019) ISSN: 1529-8019 [Electronic] United States
• PMID: 31025428 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2019 Wiley Periodicals, Inc.

Chemical References

• Glucocorticoids

Topics

• Aged
• Eosinophilia (physiopathology, therapy)
• Fasciitis (physiopathology, therapy)
• Female
• Glucocorticoids (administration & dosage)
• Humans
• Photopheresis (methods)
• Treatment Outcome