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Treatment of chronic discoid lupus erythematosus with an oral gold compound (auranofin).

Abstract
Twenty-three patients with severe longstanding discoid lupus erythematosus, unresponsive to conventional treatments, were treated with oral gold in a multicentre open study. Nineteen patients showed clinical improvement and in four of these there was complete resolution of lesions. Adverse reactions were generally mild and self limiting.
AuthorsK Dalziel, G Going, P H Cartwright, R Marks, G W Beveridge, N R Rowell
JournalThe British journal of dermatology (Br J Dermatol) Vol. 115 Issue 2 Pg. 211-6 (Aug 1986) ISSN: 0007-0963 [Print] England
PMID3091062 (Publication Type: Clinical Trial, Journal Article)
Chemical References
  • Aurothioglucose
  • Auranofin
  • Gold
Topics
  • Adolescent
  • Adult
  • Aged
  • Auranofin
  • Aurothioglucose (adverse effects, analogs & derivatives, therapeutic use)
  • Chronic Disease
  • Clinical Trials as Topic
  • Female
  • Gold (analogs & derivatives)
  • Humans
  • Lupus Erythematosus, Discoid (drug therapy)
  • Male
  • Middle Aged

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