[Assessment of quality of life and treatment adherence in patients with dizziness treated with vasobral].

Abstract

AIM:

To study indicators of quality of life and adherence to treatment with vazobral in patients with dizziness of vascular genesis.

MATERIAL AND METHODS:

Vazobral was administered to 330 patients with vertigo due to cerebrovascular disease for 3 months during a non-inferiority, open-label study. Quality of life (measured using VAS and the second part of the EQ-5D questionnaire), severity and frequency of dizziness attacks (using VAS), the overall effectiveness of treatment on the basis of objective (according to the doctor) and subjective (using CGI) assessments, treatment adherence were evaluated.

RESULTS AND CONCLUSION:

The positive effect of vazobral was reported by 320 patients (97.0%), 223 of them (67.6%) indicated a decrease in the frequency of episodes of dizziness by at least 50%, and 95 patients (28.8%) had complete relief of dizziness. Two hundred and sixty-two (79.4%) patients took the drug in full accordance with recommendations. Patients living alone missed drug intake more often. Improvement of quality of life was noted in 326 (98.8%) patients, scores for all domains of the questionnaire EQ-5D at baseline and in the end of the study were 50.8±18.1 and 78.8±14.7%, respectively (p<0.001). The tolerability of treatment was characterized by good tolerability.

• Authors: A V Lebedeva, P R Kamchatnov, S G Burd, S V Prikazchikov, A E Cherkasova, T Yu Solovyeva
• Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (Zh Nevrol Psikhiatr Im S S Korsakova) 2019 Vol. 119 Issue 2 Pg. 28-34 ISSN: 1997-7298 [Print] Russia (Federation)
• Vernacular Title: Otsenka kachestva zhizni i priverzhennosti lecheniiu preparatom vazobral patsientov s golovokruzheniem.
• PMID: 30874523 (Publication Type: Journal Article)

Chemical References

• Drug Combinations
• Dihydroergotoxine
• Caffeine
• Vasobral

Topics

• Caffeine (therapeutic use)
• Dihydroergotoxine (therapeutic use)
• Dizziness (drug therapy)
• Drug Combinations
• Humans
• Quality of Life
• Surveys and Questionnaires
• Treatment Adherence and Compliance
• Vertigo