Mucuna Pruriens Combined with Carbidopa in Parkinson's Disease: A Case Report.

Abstract

We present a 48-year-old woman with Parkinson's disease in whom carbidopa was added to Mucuna pruriens, resulting in marked motor improvement (documented on video and using MDS-UPDRS motor scores). This case report shows that adding a dopa-decarboxylase inhibitor (DDCI) to Mucuna pruriens could fit well in a personalized approach for patients who are reluctant to start levodopa. Meanwhile, larger trials with a longer follow-up are needed to establish the true effects and tolerability of Mucuna pruriens plus a DDCI.

• Authors: Danique L M Radder, Andreas T Tiel Groenestege, Inge Boers, Eline W Muilwijk, Bastiaan R Bloem
• Journal: Journal of Parkinson's disease (J Parkinsons Dis) Vol. 9 Issue 2 Pg. 437-439 ( 2019) ISSN: 1877-718X [Electronic] Netherlands
• PMID: 30856121 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Video-Audio Media)

Chemical References

• Aromatic Amino Acid Decarboxylase Inhibitors
• Plant Preparations
• Carbidopa

Topics

• Aromatic Amino Acid Decarboxylase Inhibitors (therapeutic use)
• Carbidopa (therapeutic use)
• Drug Therapy, Combination
• Female
• Humans
• Middle Aged
• Mucuna
• Parkinson Disease (drug therapy)
• Patient Preference
• Phytotherapy
• Plant Preparations (therapeutic use)