The Comprehensive Management of Cerebellar Ataxia in Adults.

Abstract

PURPOSE OF REVIEW:

In this review, we present the multidisciplinary approach to the management of the many neurological, medical, social, and emotional issues facing patients with cerebellar ataxia.

RECENT FINDINGS:

Our holistic approach to treatment, developed over the past 25 years in the Massachusetts General Hospital Ataxia Unit, is centered on the compassionate care of the patient and their family, empowering them through engagement, and including the families as partners in the healing process. We present the management of ataxia in adults, beginning with establishing an accurate diagnosis, followed by treatment of the multiple symptoms seen in cerebellar disorders, with a view to maximizing quality of life and effectively living with the consequences of ataxia. We discuss the importance of a multidisciplinary approach to the management of ataxia, including medical and non-medical management and the evidence base that supports these interventions. We address the pharmacological treatment of ataxia, tremor, and other associated movement disorders; ophthalmological symptoms; bowel, bladder, and sexual symptoms; orthostatic hypotension; psychiatric and cognitive symptoms; neuromodulation, including deep brain stimulation; rehabilitation including physical therapy, occupational therapy and speech and language pathology and, as necessary, involving urology, psychiatry, and pain medicine. We discuss the role of palliative care in late-stage disease. The management of adults with ataxia is complex and a team-based approach is essential.

• Authors: Christopher D Stephen, Kate T Brizzi, Marc A Bouffard, Pablo Gomery, Stacey L Sullivan, Julie Mello, Julie MacLean, Jeremy D Schmahmann
• Journal: Current treatment options in neurology (Curr Treat Options Neurol) Vol. 21 Issue 3 Pg. 9 (Feb 21 2019) ISSN: 1092-8480 [Print] United States
• PMID: 30788613 (Publication Type: Journal Article, Review)