Thymoma-associated Myasthenia Gravis in a Young Adult with Development of Paraneoplastic Limbic Encephalitis and Systemic Lupus Erythematosus Post-thymectomy: A Case Report.

Abstract

We report a young adult with thymoma-associated myasthenia gravis (MG) who, following thymectomy, developed paraneoplastic limbic encephalitis (LE) and systemic lupus erythematosus (SLE). Although thymomas commonly co-occur with MG, LE is an uncommon autoimmune sequela. Herein, we discuss the pathophysiology of paraneoplastic LE and its management. Our report also highlights an unusual case of a thymoma patient who presented with multiple autoimmune disorders. The treatment of such a patient is therefore challenging and requires care from multiple specialized teams.

• Authors: Robin Liu, A Rashid Dar, Keng Yeow Tay, Mike W Nicolle, Richard I Inculet
• Journal: Cureus (Cureus) Vol. 10 Issue 11 Pg. e3581 (Nov 13 2018) ISSN: 2168-8184 [Print] United States
• PMID: 30656085 (Publication Type: Case Reports)