Technical Considerations for Lung Transplantation in Kartagener's Syndrome.

Abstract

Kartagener's syndrome is a rare genetic disorder of ciliated epithelial cells associated with recurrent respiratory tract infections, bronchiectasis, and situs inversus. In some patients, the accumulation of airway secretions and recurrent infections lead to end-stage lung disease, for which lung transplantation is the only effective treatment. Anatomical variations, such as dextrocardia and pulmonary situs inversus, make the procedure challenging, yet feasible with certain technical modifications and careful preparation of donor lungs. We report a case of bilateral lung transplantation without the use of cardiopulmonary bypass in a patient with Kartagener's syndrome while describing important technical details of the operation.

• Authors: Jason M Gauthier, Tsuyoshi Takahashi, Andrew J Bierhals, Steven L Brody, Ramsey R Hachem, Chad A Witt, Derek E Byers, Roger D Yusen, Elbert P Trulock, Patrick R Aguilar, Ruben G Nava, Benjamin D Kozower, Bryan F Meyers, G Alexander Patterson, Daniel Kreisel, Varun Puri
• Journal: The Annals of thoracic surgery (Ann Thorac Surg) Vol. 107 Issue 5 Pg. e337-e339 (05 2019) ISSN: 1552-6259 [Electronic] Netherlands
• PMID: 30612988 (Publication Type: Case Reports, Journal Article, Research Support, N.I.H., Extramural)
• Copyright: Copyright © 2019 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Topics

• Cardiopulmonary Bypass
• Humans
• Kartagener Syndrome (surgery)
• Lung Transplantation (methods)
• Male
• Middle Aged