A suppurative thyroiditis and perineal subcutaneous abscess related with aspergillus fumigatus: a case report and literature review.

Abstract

BACKGROUND:

Invasive aspergillosis is a complication in immunocompromised patients and commonly detected in patients with hematological malignancies, which mostly affect the lungs. Because of its high iodine content, rich blood supply and capsule, the thyroid is considered to be less prone to microbial invasion thus most infectious thyroiditis cases are caused by bacteria. However, a few case reports have described thyroid gland aspergilloses, most of which were due to disseminated invasive aspergillosis.

CASE PRESENTATION:

We first report a case of thyroid gland and subcutaneous labium majus aspergillosis in a Chinese patient who received long-term glucocorticoid treatment for systemic lupus erythematosus (SLE) and lupus nephritis, and then we reviewed 36 articles describing similar aspergillus infections in 41 patients.

CONCLUSION:

We included 29 cases of diagnosed aspergillus thyroiditis and analyzed clinical findings, treatments and outcomes to provide clinical information for diagnosis and prognosis of thyroiditis caused by Aspergillus fumigatus.

• Authors: Jiaying Tan, Jun Shen, Yong Fang, Liping Zhu, Yang Liu, Ye Gong, Hechen Zhu, Zupeng Hu, Gang Wu
• Journal: BMC infectious diseases (BMC Infect Dis) Vol. 18 Issue 1 Pg. 702 (Dec 27 2018) ISSN: 1471-2334 [Electronic] England
• PMID: 30587135 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Antifungal Agents
• Voriconazole

Topics

• Abscess (diagnosis, drug therapy, microbiology)
• Antifungal Agents (therapeutic use)
• Aspergillosis (complications, diagnosis, drug therapy)
• Aspergillus fumigatus (isolation & purification)
• Dermatomycoses (complications, diagnosis, drug therapy, microbiology)
• Female
• Humans
• Immunocompromised Host
• Invasive Fungal Infections (complications, diagnosis, drug therapy)
• Lupus Erythematosus, Systemic (complications, drug therapy, microbiology)
• Middle Aged
• Perineum (microbiology, pathology)
• Suction
• Thyroiditis, Suppurative (diagnosis, drug therapy, microbiology, surgery)
• Voriconazole (therapeutic use)