Alternative to Avoid Tooth Discoloration after Regenerative Endodontic Procedure: A Systematic Review.

Abstract

This systematic review aimed to evaluate whether alternative materials to conventional triple antibiotic paste (TAP - metronidazole, ciprofloxacin, and minocycline) and grey mineral trioxide aggregate (GMTA) could avoid tooth discoloration in teeth submitted to Regenerative Endodontic Procedure (REP). It was also investigated if dental bleaching is able to reverse the color of darkened teeth due to REP. The search was conducted in four databases (Medline via PubMed, Scopus, ISI Web of Science and BVS - Virtual health library), following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The retrieved papers were uploaded in the software EndNoteTM and two reviewers independently selected the studies and extracted the data. Only studies in humans (case reports, case series, clinical trials) were included in the review. From 1,122 potentially eligible studies, 83 were selected for full-text analysis, and 38 were included in the review. The included studies were mainly case reports (76.3 %). The studies described a total of 189 teeth submitted to REP. From these, about 54% of teeth presented some degree of discoloration. Most teeth presenting color alteration were treated with TAP, especially when combined with GMTA. Only three studies performed dental bleaching to restore the color of teeth and neither bleaching technique was able to restore the original color of the crowns. The use of alternative materials to TAP and GMTA, such as double antibiotic paste or Ca(OH)2 pastes and white mineral trioxide aggregate or BiodentineTM, reduces the occurrence of tooth discoloration.

• Authors: Luciane Geanini Pena Dos Santos, Luiz Alexandre Chisini, Camila Guerner Springmann, Beatriz Dulcineia Mendes de Souza, Fernanda Geraldo Pappen, Flávio Fernando Demarco, Mara Cristina Santos Felippe, Wilson Tadeu Felippe
• Journal: Brazilian dental journal (Braz Dent J) 2018 Sep-Oct Vol. 29 Issue 5 Pg. 409-418 ISSN: 1806-4760 [Electronic] Brazil
• PMID: 30517438 (Publication Type: Journal Article, Systematic Review)

Chemical References

• Aluminum Compounds
• Anti-Bacterial Agents
• Calcium Compounds
• Drug Combinations
• Oxides
• Root Canal Filling Materials
• Silicates
• mineral trioxide aggregate

Topics

• Aluminum Compounds (adverse effects)
• Anti-Bacterial Agents (adverse effects)
• Calcium Compounds (adverse effects)
• Drug Combinations
• Humans
• Oxides (adverse effects)
• Regenerative Endodontics
• Root Canal Filling Materials (adverse effects)
• Silicates (adverse effects)
• Tooth Bleaching
• Tooth Discoloration (chemically induced, prevention & control)