Radiotherapy and pasireotide treatment of a growth hormone producing pituitary tumor in a diabetic dog.

Abstract

An 8-year-old castrated male border terrier dog was diagnosed with acromegaly resulting from a growth hormone secreting pituitary tumor. Sixteen daily fractions of radiation therapy were delivered followed, approximately 1 year later, by administration of pasireotide. The aforementioned treatment was considered effective and should be further evaluated in similar cases.

• Authors: Francesco Zublena, Alice Tamborini, Carmel T Mooney, Susan M North, Monika A Lobacz, Dan Andrew, Vanessa Woolhead, Heather Covey, Herbert A Schmid, David B Church, Stijn J M Niessen
• Journal: The Canadian veterinary journal = La revue veterinaire canadienne (Can Vet J) Vol. 59 Issue 10 Pg. 1089-1093 (10 2018) ISSN: 0008-5286 [Print] Canada
• PMID: 30510314 (Publication Type: Case Reports, Journal Article)

Chemical References

• Hormones
• Somatostatin
• pasireotide

Topics

• Acromegaly (etiology, veterinary)
• Adenoma (drug therapy, radiotherapy, veterinary)
• Animals
• Diabetes Mellitus (drug therapy, veterinary)
• Dog Diseases (drug therapy, radiotherapy)
• Dogs
• Growth Hormone-Secreting Pituitary Adenoma (drug therapy, radiotherapy, veterinary)
• Hormones (therapeutic use)
• Male
• Somatostatin (analogs & derivatives, therapeutic use)
• Treatment Outcome