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Bupropion-Related Exacerbation of Tic Disorder in an Adult: A Case Report.

Abstract
Bupropion is antidepressant and a smoking cessation aid medication related to dopaminergic activity. We report for the first time a case of an older adult with a known tic disorder, which was in remission but exacerbated during treatment with bupropion. It has been reported that other dopaminergic compounds such as methylphenidate can exacerbate tic disorder. Clinicians should be aware of this potential adverse effect when prescribing bupropion to adults with tic and other motor disorders.
AuthorsIdo Lurie, Ori Ganor, Gad Mayer
JournalClinical neuropharmacology (Clin Neuropharmacol) 2019 Jan/Feb Vol. 42 Issue 1 Pg. 19 ISSN: 1537-162X [Electronic] United States
PMID30499776 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antidepressive Agents, Second-Generation
  • Delayed-Action Preparations
  • Bupropion
Topics
  • Aged
  • Antidepressive Agents, Second-Generation (administration & dosage, adverse effects)
  • Bupropion (administration & dosage, adverse effects)
  • Delayed-Action Preparations
  • Humans
  • Male
  • Tic Disorders (chemically induced)

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