[A sulfadiazine-tetroxoprim combination (co-tetroxazine) in the treatment of the acute exacerbation of chronic bronchitis].

Abstract

After considering the bacterial flora which is most common in relapses in patients with bronchitis, 40 patients with chronic bronchitis have been treated with tetroxoprim a recently synthetized benzyl pyrimidine associated with sulfadiazine. One 350 mg tablet was administered every 12 hours for different periods, from 7 to 14 days. This study has shown how tetroxoprim has a wide antibacterial range, how it is well tolerated and extremely powerful in treating relapses of chronic infections in bronchi.

• Authors: M G Gambaro, P Genoni, D Berra
• Journal: Minerva medica (Minerva Med) Vol. 79 Issue 7 Pg. 563-8 (Jul 1988) ISSN: 0026-4806 [Print] Italy
• Vernacular Title: L'associazione sulfadiazina-tetroxoprim (co-tetroxazina) nel trattamento delle riacutizzazioni delle broncopatie croniche.
• PMID: 3043259 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Anti-Infective Agents
• Pyrimidines
• Sulfadiazine
• tetroxoprim

Topics

• Adult
• Aged
• Anti-Infective Agents (therapeutic use)
• Bronchitis (drug therapy, physiopathology)
• Chronic Disease
• Drug Therapy, Combination
• Female
• Humans
• Male
• Middle Aged
• Pyrimidines (administration & dosage, therapeutic use)
• Sulfadiazine (administration & dosage, therapeutic use)