Treatment of focal dystonia involving multiple muscles with a single injection of botulinum toxin A to 1 muscle: A case report.

Abstract

RATIONALE:

Botulinum toxin A (BTX-A) injection is effective in treating focal dystonia. However, there are no prior reports regarding the treatment of progressive focal dystonia by a single BTX-A injection that affect a distant muscle.

PATIENT CONCERNS:

A 19-year-old male was referred to the rehabilitation clinic with a complaint of involuntary movement in his left big toe. The involuntary movement pattern was initially observed in the abduction direction only; however, it progressed to irregular mixed patterns in the flexion and abduction directions.

DIAGNOSES:

In needle electromyography, abnormal dystonic patterns were observed in the left abductor hallucis (AH), flexor hallucis longus, and flexor hallucis brevis muscles.

INTERVENTIONS AND OUTCOMES:

These symptoms resolved with a single BTX-A injection to the AH muscle.

LESSONS:

In this case, a single BTX-A injection to 1 muscle for treating progressive focal dystonia was effective on a distant noninjected muscle.

• Authors: Sung Young Lee, Hyeok Dong Lee, Young-Shin Cho, Seung Hoon Han
• Journal: Medicine (Medicine (Baltimore)) Vol. 97 Issue 42 Pg. e12785 (Oct 2018) ISSN: 1536-5964 [Electronic] United States
• PMID: 30334967 (Publication Type: Case Reports, Journal Article)

Chemical References

• Neuromuscular Agents
• Botulinum Toxins, Type A

Topics

• Botulinum Toxins, Type A (administration & dosage)
• Dystonic Disorders (drug therapy, physiopathology)
• Foot (physiopathology)
• Hallux (physiopathology)
• Humans
• Injections, Intramuscular
• Male
• Muscle, Skeletal (drug effects, physiopathology)
• Neuromuscular Agents (administration & dosage)
• Treatment Outcome
• Young Adult