Is maintenance treatment in adult acne important? Benefits from maintenance therapy with adapalene, and low doses of alpha and beta hydroxy acids.

Abstract

Background: Adult acne is a chronic disease with uncontrolled exacerbations, associated with a psychological burden of the patient and medical expenses. Aims: The aim of the study was to check the efficacy of maintenance therapy of adult acne. It is essential part of treatment as adult acne usually has a long-lasting and recurring course. Methods: In the study, the efficacy of maintenance therapy in patients with adult acne is evaluated. In this study, 100 patients (aged 25-39 years of age) with mild and moderate adult acne were enrolled. Results: The maintenance therapy (adapalene 0.1% three times a week and low doses of alpha and beta hydroxy acids) led to a significant decrease in the number of acne lesions (from 31.3 to 12.25; p < .001) and severity of seborrhea (p < .001). Conclusions: Maintenance therapy brings significant improvements in the reduction of non-inflammatory and inflammatory lesions in patients with mild and moderate adult acne.

• Authors: Ewa Chlebus, Monika Serafin, Marcin Chlebus
• Journal: The Journal of dermatological treatment (J Dermatolog Treat) Vol. 30 Issue 6 Pg. 568-571 (Sep 2019) ISSN: 1471-1753 [Electronic] England
• PMID: 29873567 (Publication Type: Journal Article)

Chemical References

• Dermatologic Agents
• Gels
• Hydroxy Acids
• Adapalene

Topics

• Acne Vulgaris (drug therapy, pathology)
• Adapalene (therapeutic use)
• Adult
• Chronic Disease
• Dermatologic Agents (therapeutic use)
• Drug Therapy, Combination
• Female
• Gels (chemistry)
• Humans
• Hydroxy Acids (therapeutic use)
• Male
• Recurrence
• Severity of Illness Index
• Treatment Outcome