Abstract | Purpose: Methods: This prospective study included 40 eyes of 40 patients with nonischemic BRVO and 31 eyes of 31 patients with nonischemic CRVO who received IDI injection as the first-line treatment for macular edema. The best-corrected visual acuity (BCVA) value before and after the treatment; intraocular pressure; optic coherence tomography findings; and all ocular examination findings, including central foveal thickness (CFT) measurement and fluorescein angiography findings, were evaluated for each patient. Results: After the IDI injection, BCVA value increased (P < 0.001) and CFT value decreased (P < 0.001) in both groups. The recurrence rates of CFT elevation after the first and the second Ozurdex injections were 65.0% and 65.3%, respectively, in patients with BRVO and 70.9% and 68.1%, respectively, in patients with CRVO. A statistically significant correlation was observed between preinjection CFT value and postinjection recurrence of CFT elevation (P = 0.017). Conclusion: Treatment with the IDI injections resulted in significant short-term improvement in CFT and BCVA values in patients with clinically significant RVO-related macular edema. Moreover, we observed that high preinjection CFT value was associated with a risk of postinjection recurrence of CFT elevation.
|
Authors | Mert Simsek, Mehmet Citirik, Serdar Ozates, Dilara Ozkoyuncu |
Journal | Indian journal of ophthalmology
(Indian J Ophthalmol)
Vol. 66
Issue 6
Pg. 831-836
(06 2018)
ISSN: 1998-3689 [Electronic] India |
PMID | 29785994
(Publication Type: Journal Article)
|
Chemical References |
- Drug Implants
- Glucocorticoids
- Dexamethasone
|
Topics |
- Dexamethasone
(administration & dosage)
- Drug Implants
- Female
- Fluorescein Angiography
- Follow-Up Studies
- Fundus Oculi
- Glucocorticoids
(administration & dosage)
- Humans
- Intravitreal Injections
- Macular Edema
(diagnosis, drug therapy, physiopathology)
- Male
- Middle Aged
- Prospective Studies
- Retinal Vein Occlusion
(complications, diagnosis)
- Time Factors
- Tomography, Optical Coherence
- Treatment Outcome
- Visual Acuity
|