Sclerosing alcohol injections for the management of intermetatarsal neuromas: A systematic review.
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| Abstract |
An intermetatarsal neuroma is a plantar digital neuritis causing metatarsalgia of the affected inter-metatarsal space. At present the evidence to support the management of the condition is poor with only some quality evidence supporting the short-term management of intermetatarsal neuromas using steroid injections. Some authors have supported the use of alcohol sclerosing intra-lesional injections to treat intermetatarsal neuromas. Following a search of the evidence 11 articles were identified. The systematic review found that alcohol injections appear to be safe although some papers report a short-term side effect of a flogistic reaction and there are variances in the alcohol concentration used and guiding verses not guiding the injection using ultrasound imaging. Some of the evidence may suggest a sclerosing histological effect of the nerve. However, all the studies reviewed present a research design offering a low level of evidence that is open to methodological biases and interpretation. Thus, this review found insufficient high-quality research evidence to afford conclusions on the management of intermetatarsal neuromas with alcohol sclerosing agent injections.
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| Authors | Derek Santos, Graeme Morrison, Andrea Coda |
| Journal | Foot (Edinburgh, Scotland) (Foot (Edinb)) Vol. 35 Pg. 36-47 (Jun 2018) ISSN: 1532-2963 [Electronic] Scotland |
| PMID | 29778841 (Publication Type: Journal Article, Systematic Review) |
| Copyright | Crown Copyright © 2018. Published by Elsevier Ltd. All rights reserved. |
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