Consecutive diabetic patients with ischemic FUs who referred to our
Diabetic Foot Centre were prospectively included. All patients underwent a preset
limb salvage protocol including peripheral revascularization. According to the presence of HF and D, they were divided in four groups: group 1 without HF and without D defined as ischemic foot (IF); group 2 with HF and without D defined as heart ischemic foot (H-IF); group 3 without HF and with D defined as renal ischemic foot (R-IF); group 4 with HF and with dialysis defined as heart-renal foot (HR-IF). Survival with
limb salvage, survival with major
amputation and death were reported after 1 year of follow-up.
RESULTS: 136 patient have been included: 66 with IF, 26 with H-IF, 24 with R-IF and 20 with HR-IF. The mean age was 68,9 ± 9,7 years, the diabetes duration 20,7 ± 11,6 years, the mean HbA1c 62,7 ± 22,3 mmol/mol. 103/136 (75,7%) survived with
limb salvage, 10/136 (7,4%) survived with major
amputation, 23/136 (16,9%) died. The outcomes for group IF patients, H-IF, R-IF and HR-IF were respectively: survival with
limb salvage (92,4%, 61,5%, 79,2% and 35%), survival with major
amputation (6,1%, 7,7%, 8,3% and 10%), death (1,5%, 30,8%, 12,5% and 55%) χ = 0.0001.
Heart failure was an independent predictor of death.
DISCUSSION: