Abstract | OBJECTIVE: DESIGN/SETTING/PATIENTS: One hundred consecutive patients with cleft palate who underwent a von Langenbeck or 2-flap palatoplasty and intravelar veloplasty at a tertiary medical center by the 2 senior authors from 2010 to 2015 were reviewed. INTERVENTIONS: OUTCOMES MEASURED: RESULTS: The treatment groups were comprised of 40 patients who received IV acetaminophen, 22 PR acetaminophen, and 35 none. Concerning demographic data, there was no statistical difference between treatment groups. There was no statistically significant difference for opioid intake, although both IV and PR acetaminophen groups had decreased pain scores ( P = .029). There was no difference in oral intake ( P = .13) or length of stay ( P = .31) between treatment groups. CONCLUSION: In this study, intraoperative administration of acetaminophen was associated with decreased pain scores, but no opioid-sparing effect. As other studies have shown an opioid-sparing effect with postoperative acetaminophen, we recommend withholding the intraoperative dose and beginning therapy in the immediate postoperative period.
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Authors | Logan Carr, Megan Gray, Brad Morrow, Morgan Brgoch, Donald Mackay, Thomas Samson |
Journal | The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
(Cleft Palate Craniofac J)
Vol. 55
Issue 9
Pg. 1200-1204
(10 2018)
ISSN: 1545-1569 [Electronic] United States |
PMID | 29578803
(Publication Type: Journal Article)
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Chemical References |
- Analgesics, Non-Narcotic
- Analgesics, Opioid
- Acetaminophen
- Morphine
- Oxycodone
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Topics |
- Acetaminophen
(administration & dosage)
- Analgesics, Non-Narcotic
(administration & dosage)
- Analgesics, Opioid
(administration & dosage)
- Cleft Palate
(surgery)
- Female
- Humans
- Infant
- Length of Stay
(statistics & numerical data)
- Male
- Morphine
(administration & dosage)
- Oxycodone
(administration & dosage)
- Pain Measurement
- Pain, Postoperative
(drug therapy)
- Retrospective Studies
- Treatment Outcome
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