Abstract | PURPOSE: METHODS: Thirty-nine newly diagnosed, overweight (body mass index >25 kg/m2) patients with idiopathic intracranial hypertension were studied retrospectively. All patients underwent medical treatment with acetazolamide, and a weight reduction program was also offered. Patients were grouped according to their compliance with this weight reduction program into the diet-success (Group 1) and diet-failure groups (Group 2). Body mass index, papilledema, visual acuity, and perimetric mean deviation were compared at the end of the 6-month study period. RESULTS: Groups 1 and 2 did not differ regarding the baseline mean body mass index (32.63 ± 5.61, 32.35 ± 5.06 kg/m2), visual acuity (0.080 ± 0.13, 0.130 ± 0.24 logMAR), perimetric mean deviation (-9.978 ± 0.68, -12.86 ± 8.91), or papilledema grade (2.94 ± 0.22, 2.90 ± 0.30), respectively (p>0.05). During the 6 months' follow-up, Group 1 patients, who complied with both medical and diet therapy, improved significantly in all parameters, including body mass index (p<0.001), visual acuity (p=0.001), perimetric mean deviation (p=0.016), and papilledema grade (p<0.001). Conversely, Group 2 patients, who only underwent medical therapy, improved only in papilledema grade (p<0.001). However, coincident development of optic disc pallor was observed in three patients. Further, they also had significant loss in visual acuity (p=0.047) during the study period. CONCLUSION:
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Authors | Feray Koc, Mehmet Resit Isik, Nazife Sefi-Yurdakul |
Journal | Arquivos brasileiros de oftalmologia
(Arq Bras Oftalmol)
2018 Jan-Feb
Vol. 81
Issue 1
Pg. 18-23
ISSN: 1678-2925 [Electronic] Brazil |
PMID | 29538589
(Publication Type: Journal Article)
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Topics |
- Adult
- Body Mass Index
- Cross-Sectional Studies
- Female
- Humans
- Male
- Overweight
(complications, physiopathology)
- Papilledema
(diet therapy, etiology, physiopathology)
- Pseudotumor Cerebri
(diet therapy, physiopathology)
- Retrospective Studies
- Severity of Illness Index
- Treatment Outcome
- Vision Disorders
(diet therapy, etiology, physiopathology)
- Visual Acuity
(physiology)
- Visual Fields
(physiology)
- Weight Loss
(physiology)
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