Posterior scleral reinforcement using genipin-cross-linked sclera for macular hole retinal detachment in highly myopic eyes.

Abstract

BACKGROUND/AIMS:

To investigate the surgical outcomes of posterior scleral reinforcement (PSR) using genipin-cross-linked sclera to treat macular hole retinal detachment (MHRD) in highly myopic eyes.

METHODS:

Nineteen patients with high myopia (19 eyes) with MHRD were treated sequentially with genipin-cross-linked PSR and were followed at least for 1 year after the surgery. The best corrected visual acuity (BCVA), axial length (AL), optical coherence tomography (OCT) outcomes and the complications were evaluated.

RESULTS:

Macular hole was closed in 73.7% of the eyes, foveal reattachment rate was 100%. The mean logMAR BCVA improved from 1.27±0.55 preoperatively to 0.88±0.55 postoperatively. The preoperative AL (29.88±1.97 mm) was decreased (27.73±1.84 mm) after the operation (p<0.001).

CONCLUSIONS:

For at least a 1-year period of follow-up, PSR with genipin-cross-linked sclera should be considered as a preferred surgical approach to treat MHRD in highly myopic eyes, especially when foveal retinoschisis is also documented.

• Authors: Shuang-Qian Zhu, An-Peng Pan, Lin-Yan Zheng, Yue Wu, An-Quan Xue
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 102 Issue 12 Pg. 1701-1704 (12 2018) ISSN: 1468-2079 [Electronic] England
• PMID: 29519878 (Publication Type: Journal Article)
• Copyright: © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Chemical References

• Cholagogues and Choleretics
• Cross-Linking Reagents
• Iridoids
• genipin

Topics

• Adult
• Aged
• Axial Length, Eye (pathology)
• Cholagogues and Choleretics (therapeutic use)
• Cross-Linking Reagents
• Female
• Follow-Up Studies
• Humans
• Iridoids (therapeutic use)
• Male
• Middle Aged
• Myopia, Degenerative (complications, physiopathology)
• Retinal Detachment (diagnostic imaging, etiology, physiopathology, therapy)
• Retinal Perforations (diagnostic imaging, etiology, physiopathology, therapy)
• Retrospective Studies
• Sclera (drug effects)
• Tomography, Optical Coherence
• Visual Acuity (physiology)