Decitabine improves response rate and prolongs progression-free survival in older patients with newly diagnosed acute myeloid leukemia and with monosomal karyotype: A subgroup analysis of the DACO-016 trial.

• Authors: Agnieszka Wierzbowska, Ewa Wawrzyniak, Agnieszka Pluta, Tadeusz Robak, Grzegorz J Mazur, Anna Dmoszynska, Jaroslav Cermak, Albert Oriol, Daniel Lysak, Chris Arthur, Margaret Doyle, Liang Xiu, Farhad Ravandi, Hagop M Kantarjian
• Journal: American journal of hematology (Am J Hematol) Vol. 93 Issue 5 Pg. E125-E127 (05 2018) ISSN: 1096-8652 [Electronic] United States
• PMID: 29417613 (Publication Type: Clinical Trial, Phase III, Letter, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Decitabine

Topics

• Aged
• Aged, 80 and over
• Decitabine (pharmacology, therapeutic use)
• Humans
• Karyotyping
• Leukemia, Myeloid, Acute (drug therapy, genetics, mortality)
• Monosomy
• Progression-Free Survival
• Survival Analysis