Abstract | PURPOSE OF REVIEW: RECENT FINDINGS: The release of pro-inflammatory cytokines and upregulation of matrix-degrading proteins in hypercholesterolemic conditions leads to an increase in tendon stiffness and elastic modulus. The effect of hypercholesterolemia drugs, such as statins, on tendon pathology remains unclear. More insight into the relationship between HC and tendon pathology can lead to improved imaging modalities and therapeutics for tendinopathy in hypercholesterolemic patients.
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Authors | Brittany Taylor, Adnan Cheema, Louis Soslowsky |
Journal | Current rheumatology reports
(Curr Rheumatol Rep)
Vol. 19
Issue 12
Pg. 76
(Nov 04 2017)
ISSN: 1534-6307 [Electronic] United States |
PMID | 29101577
(Publication Type: Journal Article, Review)
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Chemical References |
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Topics |
- Cytokines
(metabolism)
- Elastic Modulus
- Extracellular Matrix
(metabolism, pathology)
- Humans
- Hypercholesterolemia
(metabolism, pathology)
- Hyperlipoproteinemia Type II
(metabolism, pathology)
- Tendons
(metabolism, pathology)
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