Abstract | BACKGROUND/AIMS: Patients who suffer from Dejerine-Roussy syndrome commonly experience severe poststroke hemibody pain which has historically been attributed to thalamic lesions. Despite pharmacological treatment, a significant proportion of the population is resistant to traditional therapy. Deep brain stimulation is often appropriate for the treatment of resistant populations. In this review we aim to summarize the targets that are used to treat Dejerine-Roussy syndrome and provide insight into their clinical efficacy. METHODS: In reviewing the literature, we defined stimulation success as achievement of a minimum of 50% pain relief. RESULTS: Contemporary targets for deep brain stimulation are the ventral posterior medial/ventral posterior lateral thalamic nuclei, periaqueductal/periventricular gray matter, the ventral striatum/anterior limb of the internal capsule, left centromedian thalamic nuclei, the nucleus ventrocaudalis parvocellularis internis, and the posterior limb of the internal capsule. CONCLUSIONS:
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Authors | Max Ward, Antonios Mammis |
Journal | Stereotactic and functional neurosurgery
(Stereotact Funct Neurosurg)
Vol. 95
Issue 5
Pg. 298-306
( 2017)
ISSN: 1423-0372 [Electronic] Switzerland |
PMID | 28848107
(Publication Type: Journal Article)
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Copyright | © 2017 S. Karger AG, Basel. |
Topics |
- Deep Brain Stimulation
(methods)
- Female
- Humans
- Internal Capsule
(physiopathology)
- Male
- Middle Aged
- Pain
(epidemiology, physiopathology)
- Pain Management
(methods)
- Thalamic Diseases
(epidemiology, physiopathology, therapy)
- Treatment Outcome
- Ventral Thalamic Nuclei
(physiopathology)
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