Abstract | BACKGROUND: AIM: To systematically review the literature on available pharmacotherapy to reduce output and to propose an algorithm for standard of care. METHODS: Relevant databases were systematically reviewed to identify studies on pharmacotherapy for reduction in (high-) output enterostomies or fistula. Randomised controlled trials and within subjects controlled prospective trials were included. An algorithm for standard of care was generated based on the outcomes of the systematic review. RESULTS: CONCLUSIONS: The available evidence on the efficacy of medication to reduce enterostomy or enterocutaneous fistula output is hampered by low quality studies. We propose an algorithm for standard of care output reduction in these patients.
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Authors | F E E de Vries, L F Reeskamp, O van Ruler, I van Arum, W Kuin, G Dijksta, J W Haveman, M A Boermeester, M J Serlie |
Journal | Alimentary pharmacology & therapeutics
(Aliment Pharmacol Ther)
Vol. 46
Issue 3
Pg. 266-273
(08 2017)
ISSN: 1365-2036 [Electronic] England |
PMID | 28613003
(Publication Type: Journal Article, Review, Systematic Review)
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Copyright | © 2017 John Wiley & Sons Ltd. |
Chemical References |
- Proton Pump Inhibitors
- Somatostatin
- Ranitidine
- Omeprazole
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Topics |
- Enterostomy
(methods)
- Humans
- Omeprazole
(therapeutic use)
- Proton Pump Inhibitors
(therapeutic use)
- Randomized Controlled Trials as Topic
- Ranitidine
(administration & dosage)
- Somatostatin
(administration & dosage, analogs & derivatives)
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