Abstract | OBJECTIVE: PATIENTS AND METHODS: RESULTS: A total of 221 patients with TGA were identified and 221 age- and sex-matched controls were included in the analysis. The mean duration of follow-up was 12 years in both groups (range, 0.07-29.93). Prevalence of vascular risk factors and history of seizures were similar between both groups. Previous migraine was more common in the TGA group (42 patients [19.1%] vs 12 patients [5.4%]; P<.001). There was no statistically significant difference between survival curves for the TGA group and the control group using time to any type of cerebrovascular event (log-rank P=.30), time to seizures event (log-rank P=.55), and time to cognitive impair event (log-rank P=.88) as end points. The TGA recurrence occurred in 5.4% of patients after a median interval of 4.21 years (interquartile range, 2.82-8.44). Modified Rankin scale and death rates at last follow-up were also similar between both groups. CONCLUSION: Our findings indicate that having an episode of TGA does not increase the risk of subsequent cerebrovascular events, seizures, or cognitive impairment.
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Authors | Julieta E Arena, Robert D Brown, Jay Mandrekar, Alejandro A Rabinstein |
Journal | Mayo Clinic proceedings
(Mayo Clin Proc)
Vol. 92
Issue 3
Pg. 399-405
(03 2017)
ISSN: 1942-5546 [Electronic] England |
PMID | 28185658
(Publication Type: Journal Article, Research Support, N.I.H., Extramural)
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Copyright | Copyright © 2016 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved. |
Topics |
- Aged
- Amnesia, Transient Global
(epidemiology)
- Case-Control Studies
- Cognition Disorders
(epidemiology)
- Comorbidity
- Female
- Follow-Up Studies
- Humans
- Ischemic Attack, Transient
(epidemiology)
- Male
- Middle Aged
- Minnesota
(epidemiology)
- Population Surveillance
(methods)
- Prevalence
- Risk Assessment
(methods)
- Seizures
(epidemiology)
- Stroke
(epidemiology)
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