Therapeutics for Equine Protozoal Myeloencephalitis.

Abstract

Equine protozoal myeloencephalitis is an infectious disease of the central nervous system caused by Sarcocystis neurona or Neospora hughesi. Affected horses routinely present with progressive and asymmetrical neurologic deficits. The diagnosis relies on the presence of neurologic signs, ruling out other neurologic disorders, and the detection of intrathecally derived antibodies to either S neurona and/or N hughesi. Recommended treatment is use of an FDA-approved anticoccidial drug formulation. Medical and supportive treatment is provided based on the severity of neurologic deficits and complications. This article focuses on recent data related to diagnosis, pharmacologic treatment, and prevention.

• Authors: Nicola Pusterla, Thomas Tobin
• Journal: The Veterinary clinics of North America. Equine practice (Vet Clin North Am Equine Pract) Vol. 33 Issue 1 Pg. 87-97 (Apr 2017) ISSN: 1558-4224 [Electronic] United States
• PMID: 28161037 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2016 Elsevier Inc. All rights reserved.

Chemical References

• Antiprotozoal Agents

Topics

• Animals
• Antiprotozoal Agents (therapeutic use)
• Encephalomyelitis (drug therapy, parasitology, veterinary)
• Horse Diseases (drug therapy, parasitology)
• Horses
• Neospora (isolation & purification)
• Sarcocystis (isolation & purification)
• Sarcocystosis (drug therapy, parasitology, veterinary)