A Case Report of Widespread Majocchi's Granuloma in a Patient with Systemic Lupus Erythematosus.

Abstract

Majocchi's granuloma is an intracutaneous or subcutaneous granulomatous inflammation caused by invasion of dermatophytic fungus, especially Trichophyton rubrum. This type of lesion is misdiagnosed frequently without proper auxiliary examination. Here, we report a case of widespread Majocchi's granuloma caused by T. rubrum in a 35-year-old woman with systemic lupus erythematosus for 9 years. The patient was initially misdiagnosed as SLE-associated skin lesions, which delayed her treatment and resulted in severe multiple disseminated lesions. After confirmed as Majocchi's granuloma, the patient was cured after 11-month treatment with terbinafine.

• Authors: Sitong Zhou, Yemei Yang, Kangxing Liu, Shiyun Huang, Yongxuan Hu, Xianyi Zhou
• Journal: Mycopathologia (Mycopathologia) Vol. 182 Issue 5-6 Pg. 577-581 (Jun 2017) ISSN: 1573-0832 [Electronic] Netherlands
• PMID: 28083794 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antifungal Agents
• Naphthalenes
• Terbinafine

Topics

• Adult
• Antifungal Agents (therapeutic use)
• Dermatomycoses (complications, diagnosis, drug therapy, pathology)
• Female
• Granuloma (complications, diagnosis, drug therapy, pathology)
• Histocytochemistry
• Humans
• Lupus Erythematosus, Systemic (complications, diagnosis, pathology)
• Microbiological Techniques
• Microscopy
• Naphthalenes (therapeutic use)
• Terbinafine
• Treatment Outcome
• Trichophyton (classification, isolation & purification)