Progressive Susac syndrome with bilateral visual loss and disability.

Abstract

Susac syndrome (SS) is a rare retinal-cochlear-cerebral disease with an unclear etiology. A 35-year-old man presented with sudden painless vision loss in the right eye and 2 months later in the left eye with hemiparesis, behavioral changes, and hearing loss. Ophthalmic examinations revealed multiple branch retinal artery occlusions (BRAOs) in both eyes. Brain magnetic resonance imaging showed inflammatory changes with multiple "punched-out" lesions in the corpus callosum which confirmed the diagnosis of SS. Despite intravenous and oral corticosteroid therapy, the disease progressed with the development of new BRAOs, low vision in both eyes, and disability. Prompt diagnosis and early treatment may save the vision and even patient's life.

• Authors: Morteza Entezari, Saeed Karimi, Mohammadali Feizi
• Journal: Indian journal of ophthalmology (Indian J Ophthalmol) Vol. 64 Issue 9 Pg. 678-680 (Sep 2016) ISSN: 1998-3689 [Electronic] India
• PMID: 27853020 (Publication Type: Case Reports, Journal Article)

Chemical References

• Drug Combinations
• Glucocorticoids
• Prednisolone
• Methylprednisolone

Topics

• Administration, Oral
• Adult
• Disability Evaluation
• Disease Progression
• Drug Combinations
• Fluorescein Angiography
• Glucocorticoids (therapeutic use)
• Humans
• Injections, Intravenous
• Magnetic Resonance Imaging
• Male
• Methylprednisolone (therapeutic use)
• Prednisolone (therapeutic use)
• Retinal Artery Occlusion (diagnosis, drug therapy)
• Susac Syndrome (diagnosis, drug therapy)
• Vision, Low (diagnosis, drug therapy)
• Visually Impaired Persons