Abstract | BACKGROUND: METHODS:
Short bowel syndrome equivalent to a high jejunostomy was generated in adult male hsp70:dnfgfr1-GFP zebrafish, wildtype fish exposed to tyrosine-kinase inhibitor, and wildtype fish in absence of tyrosine-kinase inhibitor. Heat shock in hsp70:dnfgfr1-GFP fish decreases fgf 1 expression. Parameters including weight, proliferation, and differentiation were evaluated after harvest in experimental and control groups. RESULTS: CONCLUSION:
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Authors | Kathy A Schall, Kathleen A Holoyda, Mubina Isani, Ching-Ling Lien, Denise Al Alam, Tracy C Grikscheit |
Journal | Surgery
(Surgery)
Vol. 161
Issue 3
Pg. 694-703
(03 2017)
ISSN: 1532-7361 [Electronic] United States |
PMID | 27771159
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2016 Elsevier Inc. All rights reserved. |
Chemical References |
- Fibroblast Growth Factor 1
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Topics |
- Animals
- Cell Proliferation
(physiology)
- Disease Models, Animal
- Enterocytes
(physiology)
- Fibroblast Growth Factor 1
(physiology)
- Intestine, Small
(metabolism, pathology)
- Male
- Short Bowel Syndrome
(etiology, metabolism, pathology)
- Signal Transduction
(physiology)
- Weight Loss
(physiology)
- Zebrafish
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