Comparison of the PEEK cage and an autologous cage made from the lumbar spinous process and laminae in posterior lumbar interbody fusion.

Abstract

BACKGROUND:

A prospective cohort study was performed to evaluate the clinical and radiological outcomes following posterior lumbar interbody fusion (PLIF) in patients treated with a PEEK cage compared to those treated with an autologous cage using the lumbar spinous process and laminae (ACSP).

METHODS:

Sixty-nine consecutive patients with lumbar degenerative disc disease were randomly assigned to either a PEEK cage (group A, n = 34) or an ACSP (group B, n = 35). Monosegmental PLIF was performed in all patients. Mean lumbar lordosis, mean disc height, visual analog scale (VAS) scores, functional outcomes, fusion rates and complication rates were recorded and compared. The patients were followed postoperatively for a minimum of 2 years.

RESULTS:

Successful radiographic fusion was documented in all patients. No flexion-extension hypermobility or pedicle screw loosening or breakage occurred during the follow-up period. No significant difference existed between the 2 groups when comparing the mean lumbar lordosis, mean disc height, visual analog scale (VAS) scores, functional outcomes, fusion rates or complication rates. Overall satisfactory results were achieved in both groups.

CONCLUSIONS:

The results suggest that the ACSP appears to be equally as safe and effective as the PEEK cage.

TRIAL REGISTRATION:

ISRCTN25558534 . Retrospectively registered 16/02/2016.

• Authors: Bin Lin, Hui Yu, Zhida Chen, Zhuanzhi Huang, Wenbin Zhang
• Journal: BMC musculoskeletal disorders (BMC Musculoskelet Disord) Vol. 17 Issue 1 Pg. 374 (08 30 2016) ISSN: 1471-2474 [Electronic] England
• PMID: 27577978 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Benzophenones
• Biocompatible Materials
• Ketones
• Polymers
• polyetheretherketone
• Polyethylene Glycols

Topics

• Adult
• Benzophenones
• Biocompatible Materials (therapeutic use)
• Bone Transplantation
• Female
• Follow-Up Studies
• Humans
• Intervertebral Disc Degeneration (surgery)
• Ketones (therapeutic use)
• Lordosis (diagnostic imaging)
• Lumbar Vertebrae (diagnostic imaging, transplantation)
• Lumbosacral Region (diagnostic imaging)
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Pain Measurement
• Pedicle Screws
• Polyethylene Glycols (therapeutic use)
• Polymers
• Prospective Studies
• Radiography
• Spinal Fusion (instrumentation, methods)
• Tomography, X-Ray Computed
• Transplantation, Autologous
• Treatment Outcome