Identification of a gammaherpesvirus belonging to the malignant catarrhal fever group of viruses in Pyrenean chamois (Rupicapra p. pyrenaica).

Abstract

High prevalence (46 %) of a gammaherpesvirus was confirmed by molecular detection in the lungs of hunted Pyrenean chamois. The partial glycoprotein B sequence up to the DNA polymerase gene showed 96.6 % nucleotide sequence identity to the Rupicapra rupicapra gammaherpesvirus 1 and 81.5 % to ovine herpesvirus 2. This novel sequence clusters within sequences derived from the malignant catarrhal fever group of viruses, and the corresponding virus is tentatively named Rupicapra pyrenaica gammaherpesvirus 1 (RpHV-1). No specific histological lesions were associated with RpHV-1, nor were any detrimental effects on host health. The epidemiological, phylogenetic and histopathological results suggest that Pyrenean chamois is the natural host of RpHV-1.

• Authors: Xavier Fernández-Aguilar, Fernando Esperón, Oscar Cabezón, Roser Velarde, Gregorio Mentaberre, Verónica Delicado, María Jesús Muñoz, Emmanuel Serrano, Santiago Lavín, Jorge Ramón López-Olvera
• Journal: Archives of virology (Arch Virol) Vol. 161 Issue 11 Pg. 3249-53 (Nov 2016) ISSN: 1432-8798 [Electronic] Austria
• PMID: 27535412 (Publication Type: Journal Article)

Chemical References

• Glycoproteins
• Viral Structural Proteins

Topics

• Animals
• Asymptomatic Infections
• Cluster Analysis
• Gammaherpesvirinae (classification, isolation & purification)
• Glycoproteins (genetics)
• Herpesviridae Infections (veterinary, virology)
• Lung (virology)
• Phylogeny
• Rupicapra (virology)
• Sequence Analysis, DNA
• Sequence Homology
• Viral Structural Proteins (genetics)