Use of specific immunoglobulins and vaccines for the management of accidental needlestick injury in the child: a practical review in the anti-vaccination movement era.

Abstract

INTRODUCTION:

Accidental needle injury is a common but still discussed problem.

OBJECTIVE:

We discuss possible options to optimize the management of injured children in light of the available literature findings.

RESULTS:

The risk of viral infection is low. However, blood investigations are mandatory, as well as appropriate counselling. Anti-HBV immunoglobulins are recommended in all unvaccinated subjects exposed to a HBsAg-positive source; however, there is no agreement regarding their administration in unvaccinated children. Use of anti-tetanus immunoglobulins in unvaccinated child with minor and clean wound is well defined; however, wound type classification in the event of needlestick injury may be difficult and subjective. There is no agreement on the routine use of antiretroviral prophylaxis.

CONCLUSION:

From a practical point of view, several unsolved issues have emerged regarding the management of the children with needlestick injury, which appear particularly relevant in the anti-vaccination movement era. International guidelines should be encouraged at this regard.

• Authors: Sara Sollai, Jessica Iacopelli, Mattia Giovannini, Manuela Prato, Luisa Galli, Maurizio de Martino, Elena Chiappini
• Journal: Journal of chemotherapy (Florence, Italy) (J Chemother) Vol. 28 Issue 5 Pg. 355-8 (Oct 2016) ISSN: 1973-9478 [Electronic] England
• PMID: 27347887 (Publication Type: Journal Article, Review)

Chemical References

• Immunoglobulins
• Vaccines

Topics

• Anti-Vaccination Movement
• Child
• Child, Preschool
• Female
• Humans
• Immunoglobulins (therapeutic use)
• Male
• Needlestick Injuries (complications, therapy)
• Vaccines (therapeutic use)
• Virus Diseases (prevention & control)