A case of focal nodular hyperplasia with a new characteristic finding on contrast-enhanced ultrasonography using Levovist.

Abstract

We used contrast-enhanced ultrasound with Levovist, a microbubble contrast agent, to diagnose a case of hepatic focal nodular hyperplasia (FNH). A new characteristic finding of heartbeat-synchronized centrifugal enhancement was discovered. We call this enhancement pattern the "sonographic fireworks sign." It is expected to be useful for diagnosing FNH, especially when the lesions are small and it is difficult to depict a spoke-wheel pattern.

• Authors: Kaoru Onoue, Yukio Miyamoto, Makiko Nishioka, Norio Nakata, Toru Sekiya, Kunihiko Fukuda
• Journal: Journal of medical ultrasonics (2001) (J Med Ultrason (2001)) Vol. 40 Issue 1 Pg. 47-50 (Jan 2013) ISSN: 1346-4523 [Print] Japan
• PMID: 27276924 (Publication Type: Journal Article)