BILATERAL COATS REACTION IN BANNAYAN-ZONANA SYNDROME: A SINGLE CASE REPORT.

Abstract

PURPOSE:

To report the clinical features of bilateral Coats reaction in a patient with Bannayan-Zonana syndrome.

METHODS:

The clinical course and retinal manifestations of a 21-year-old patient with Bannayan-Zonana syndrome and bilateral Coats reaction were studied. Retinal manifestations were documented with clinical examination, ultrawide-field color imaging, and ultrawide-field fluorescein angiography.

RESULTS:

Best-corrected visual acuities were 20/25 OD and 20/25 OS. Anterior segment examinations were normal bilaterally. The inferotemporal quadrant of the left retina demonstrated retinal telangiectasias, exudation, and a neurosensory retinal detachment extending to the mid-periphery. Fluorescein angiography demonstrated bilateral peripheral nonperfusion and vascular staining. An epiretinal membrane also involved the left macula.

CONCLUSION:

Bannayan-Zonana syndrome is an autosomal-dominant, hamartomatous disease characterized by a mutation spectrum that involves genes responsible for vascular development. Retinal vascular abnormalities and exudation can be a manifestation of this syndrome.

• Authors: Meredith R Klifto, Chandrakumar Balaratnasingam, Harold H Weissman, Lawrence A Yannuzzi
• Journal: Retinal cases & brief reports (Retin Cases Brief Rep) 2017 Summer Vol. 11 Issue 3 Pg. 286-289 ISSN: 1937-1578 [Electronic] United States
• PMID: 27228318 (Publication Type: Case Reports, Journal Article)

Topics

• Diagnosis, Differential
• Fluorescein Angiography
• Fundus Oculi
• Hamartoma Syndrome, Multiple (complications, diagnosis)
• Humans
• Male
• Retinal Telangiectasis (diagnosis, etiology)
• Visual Acuity
• Young Adult