Regain of visuospatial capacity after coenzyme Q10 in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes: a case report.

Abstract

OBJECTIVE:

MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes) is a neurodegenerative disorder caused by mitochondrial dysfunction. Multiple systems of the body, including cognitive function and heart conduction, can be affected by this disorder. We report a case with global cognitive impairment.

METHOD:

A single-case report.

RESULTS:

The patient got improved cognitive function, especially visuospatial function, under coenzyme Q10 treatment.

CONCLUSION:

First, coenzyme Q10 may give some benefit to control MELAS. Second, cognitive functions and intellectual abilities decline with disease progression. Routine neuropsychological tests should be performed.

• Authors: Che-Sheng Chu, Chin-Liang Chu, Hong-Ern Liu, Ti Lu
• Journal: Acta neuropsychiatrica (Acta Neuropsychiatr) Vol. 24 Issue 3 Pg. 186-8 (Jun 2012) ISSN: 0924-2708 [Print] England
• PMID: 26953014 (Publication Type: Journal Article)