Intravitreal ketorolac for the treatment of chronic cystoid macular edema after cataract surgery.

Abstract

PURPOSE:

To report two cases of chronic postoperative cystoid macular edema, resistant to topical therapy, treated with consecutive intravitreal injections of ketorolac tromethamine.

METHODS:

Four daily intravitreal injections of 500 μg/0.05 mL of ketorolac were given to each patient. Complete clinical examination and OCT were performed before every injection, 1, 2, 3 weeks, and 1, 3, and 6 months after the last injection. Fluorescein angiography was performed at baseline examination, 1, 3, and 6 months after the last injection.

RESULTS:

In both cases, the edema regressed and visual acuity increased. At 6 months after the last injection, the leakage was significantly reduced at the fluorescein angiography.

DISCUSSION:

Both cases responded favorably to the consecutive intravitreal administration of ketorolac tromethamine. The long-lasting remission of the macular edema in these chronic cases underlines the therapeutic potential of these agents when delivered intravitreally.

• Authors: Miltiadis K Tsilimbaris, Chrysanthi Tsika, George D Kymionis
• Journal: Therapeutics and clinical risk management (Ther Clin Risk Manag) Vol. 12 Pg. 177-82 ( 2016) ISSN: 1176-6336 [Print] New Zealand
• PMID: 26929630 (Publication Type: Journal Article)