Abstract |
Cerebral arteriovenous malformations (AVM) are traditionally considered primary congenital lesions that result from embryological aberrations in vasculogenesis. Recent insights, however, suggest that these lesions may be secondary to a vascular insult such as ischemia or trauma. Herein, the authors present a rare case of a secondary cerebral AVM, occurring in a young girl who received prior cranial radiation therapy. At age 3years, she underwent surgical resection, chemotherapy, and photon radiation therapy for treatment of a fourth ventricular ependymoma. At age 19years, she developed new onset seizures and was found to have a left medial temporal lobe AVM. Her seizures were managed successfully with anti-epileptic medications and the AVM was treated with proton radiation therapy. This case highlights a rare but possible vascular sequela of radiation therapy and adds to the growing body of evidence that cerebral AVM may arise as secondary lesions.
|
Authors | Matthew J Koch, Pankaj K Agarwalla, Christopher J Stapleton, Christopher S Ogilvy, Jay S Loeffler |
Journal | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
(J Clin Neurosci)
Vol. 28
Pg. 162-7
(Jun 2016)
ISSN: 1532-2653 [Electronic] Scotland |
PMID | 26860850
(Publication Type: Case Reports, Journal Article)
|
Copyright | Copyright © 2015 Elsevier Ltd. All rights reserved. |
Topics |
- Cerebral Angiography
- Female
- Humans
- Infant
- Intracranial Arteriovenous Malformations
(classification, diagnostic imaging, etiology)
- Radiosurgery
(adverse effects)
- Terminology as Topic
|