[Partial lipodystrophy and membranoproliferative glomerulonephritis. Apropos of a case].

Abstract

We have studied a girl seven and a half years old with a renal disease manifested by proteinuria and nephrotic syndrome combined with initial macroscopic hematuria normal blood pressure and persistent depression of the complement C3 levels with the complement activating gamma globulin (C3 Nef) present in serum. The anatomopathological study showed findings of membranoproliferative glomerulonephritis type II with intramembranous deposit (dense deposit disease). An unusual association with partial lipodystrophy was present in this case. A follow-up of five years, and a few considerations about etiopathogenic theories were presented.

• Authors: M J Martínez Debora, M Vázquez Martul, J L Ecija Peiró, J González Pérez, J Lirio Rodríguez, I González Mediero
• Journal: Anales espanoles de pediatria (An Esp Pediatr) Vol. 30 Issue 6 Pg. 499-502 (Jun 1989) ISSN: 0302-4342 [Print] Spain
• Vernacular Title: Lipodistrofia parcial y glomerulonefritis membranoproliferativa. A propósito de un caso.
• PMID: 2679278 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Complement C3
• Complement C3 Nephritic Factor

Topics

• Child
• Complement C3 (analysis)
• Complement C3 Nephritic Factor (analysis)
• Female
• Glomerulonephritis, Membranoproliferative (complications)
• Humans
• Lipodystrophy (complications)