Rivaroxaban-Induced Nontraumatic Spinal Subdural Hematoma: An Uncommon Yet Life-Threatening Complication.

Abstract

In the last decade, the desire for safer oral anticoagulants (OACs) led to the emergence of newer drugs. Available clinical trials demonstrated a lower risk of OACs-associated life-threatening bleeding events, including intracranial hemorrhage, compared to warfarin. Nontraumatic spinal hematoma is an uncommon yet life-threatening neurosurgical emergency that can be associated with the use of these agents. Rivaroxaban, one of the newly approved OACs, is a direct factor Xa inhibitor. To the best of our knowledge, to date, only two published cases report the incidence of rivaroxaban-induced nontraumatic spinal subdural hematoma (SSDH). Our case is the third one described and the first one to involve the cervicothoracic spine.

• Authors: Mazen Zaarour, Samer Hassan, Nishitha Thumallapally, Qun Dai
• Journal: Case reports in hematology (Case Rep Hematol) Vol. 2015 Pg. 275380 ( 2015) ISSN: 2090-6560 [Print] United States
• PMID: 26543654 (Publication Type: Journal Article)