Abstract |
Food allergy is increasing in prevalence; as a result, there is intense focus on developing safe and effective therapies. Current methods of specific immunotherapy include oral, sublingual, and epicutaneous, while nonspecific methods that have been investigated include: Chinese herbal medicine, probiotics, and anti-IgE antibodies. Although some studies have demonstrated efficacy in inducing desensitization, questions regarding safety and the potential for achieving immune tolerance remain. Although some of these therapies demonstrate promise, further investigation is required before their incorporation into routine clinical practice.
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Authors | Bruce J Lanser, Benjamin L Wright, Kelly A Orgel, Brian P Vickery, David M Fleischer |
Journal | Pediatric clinics of North America
(Pediatr Clin North Am)
Vol. 62
Issue 6
Pg. 1531-49
(Dec 2015)
ISSN: 1557-8240 [Electronic] United States |
PMID | 26456449
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Review)
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Copyright | Copyright © 2015 Elsevier Inc. All rights reserved. |
Chemical References |
- Anti-Allergic Agents
- Omalizumab
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Topics |
- Anaphylaxis
(prevention & control)
- Anti-Allergic Agents
(therapeutic use)
- Child
- Desensitization, Immunologic
- Food Hypersensitivity
(therapy)
- Humans
- Immunotherapy
(methods)
- Omalizumab
(therapeutic use)
- Patient Education as Topic
- Probiotics
(therapeutic use)
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