Abstract | BACKGROUND: To determine the anti-dysenteric, phytochemicals and antioxidative properties of the root extracts of Hydnora africana. The use of plants for the treatment of dysentery and other diseases in traditional medicine has increased on the basis of these rich traditional medicine systems. Series of pharmacological tests are recommended since the aetiology of many diseases may be due to more than one factor. METHODS: The agar well diffusion method was used to determine the susceptibility of bacterial strains to crude extracts of the plant. The minimum inhibitory concentration was determined by the microdilution test. The presence of phytochemicals and antioxidant was also assessed using standard methods. RESULTS: CONCLUSIONS: The methanol and acetone extracts of H. africana exhibited a significant antibacterial and antioxidant activities, suggesting the presence of either good bioactive potency or the high concentration of the active principle in the extracts which may serve as a guide for selecting bio- medicinal substances of plant origin in antidysenteric drugs.
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Authors | O A Wintola, A J Afolayan |
Journal | BMC complementary and alternative medicine
(BMC Complement Altern Med)
Vol. 15
Pg. 307
(Sep 04 2015)
ISSN: 1472-6882 [Electronic] England |
PMID | 26335685
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Bacterial Agents
- Antioxidants
- Phytochemicals
- Plant Extracts
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Topics |
- Anti-Bacterial Agents
(chemistry, pharmacology)
- Antioxidants
(chemistry, pharmacology)
- Bacteria
(drug effects)
- Magnoliopsida
(chemistry)
- Medicine, African Traditional
- Microbial Sensitivity Tests
- Phytochemicals
(chemistry, pharmacology)
- Plant Extracts
(chemistry, pharmacology)
- Plant Roots
(chemistry)
- South Africa
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