Pericarditis as the Presenting Feature of Graves Disease in a Pediatric Patient.

Abstract

Pericarditis is a rare presentation of thyrotoxicosis associated with Graves disease. This association has not been previously described in the pediatric literature. We report a 17-year-old male patient who presented with chest pain, dyspnea, and tachycardia. He was found to have diffuse ST-segment elevation consistent with pericarditis. At presentation, he was noted to have bilateral proptosis. Abnormal thyroid function studies and an elevated thyroid-stimulating hormone receptor antibody level confirmed the diagnosis of Graves thyrotoxicosis. The patient was treated with anti-inflammatory and antithyroid agents and improved in time. We discuss previously reported cases of Graves disease-associated pericarditis in adults, potential etiologies, and management strategies.

• Authors: Danielle Cullen, Neil Munjal, Hannah Chalal, Sriram Ramgopal, Emir Tas, Selma Witchel
• Journal: Pediatric emergency care (Pediatr Emerg Care) Vol. 33 Issue 4 Pg. 268-270 (Apr 2017) ISSN: 1535-1815 [Electronic] United States
• PMID: 26181502 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Inflammatory Agents
• Antithyroid Agents

Topics

• Adolescent
• Anti-Inflammatory Agents (therapeutic use)
• Antithyroid Agents (therapeutic use)
• Exophthalmos (drug therapy, etiology)
• Graves Disease (diagnosis, drug therapy)
• Humans
• Male
• Pericarditis (diagnosis, drug therapy)
• Treatment Outcome