Fish Malodour syndrome in a child.

Abstract

Body odour can be a manifestation of several metabolic diseases. Diagnosis may be difficult because the disease is often unknown to the doctor. We present a child observed in a general paediatric clinic for bad body odour after eating fish. Given the suspicion of trimethylaminuria, molecular study of flavin mono-oxygenase 3 gene was requested. A pathogenic mutation and polymorphism were identified, which could explain the complaint. Dietary and hygienic measures were imposed with symptom improvement.

• Authors: Alexandra Oliveira, Ana Faria, Mónica Oliva
• Journal: BMJ case reports (BMJ Case Rep) Vol. 2015 (Apr 13 2015) ISSN: 1757-790X [Electronic] England
• PMID: 25870212 (Publication Type: Case Reports, Journal Article)
• Copyright: 2015 BMJ Publishing Group Ltd.

Chemical References

• Methylamines
• Oxygenases
• dimethylaniline monooxygenase (N-oxide forming)
• trimethyloxamine
• trimethylamine

Topics

• Child, Preschool
• Diagnosis, Differential
• Diet Therapy (methods)
• Female
• Humans
• Hygiene
• Metabolism, Inborn Errors (diagnosis, genetics, therapy)
• Methylamines (metabolism, urine)
• Mutation
• Oxygenases (genetics, metabolism)
• Polymorphism, Genetic