Pregnancy complicated by cyclic vomiting syndrome successfully treated with amitriptyline.

Abstract

BACKGROUND:

Some reports suggest that pregnancy leads to exacerbation of cyclic vomiting syndrome. We report a case of pregnancy complicated by cyclic vomiting syndrome that was successfully resolved with amitriptyline, with the subsequent birth of a healthy term neonate.

CASE:

A 27-year-old pregnant woman with cyclic vomiting syndrome was referred to our hospital at 12 weeks of gestation. After excluding other diagnoses, we administered amitriptyline, which had been discontinued temporarily at the time of pregnancy diagnosis. Once a therapeutic dose was achieved, her vomiting attacks ceased and the remainder of her prenatal course was uneventful. At 40 weeks of gestation, she delivered a female neonate.

CONCLUSION:

Prevention of vomiting attacks using appropriate agents is essential for the management of pregnancies complicated by cyclic vomiting syndrome.

• Authors: Hanako Tamai, Masato Kinugasa
• Journal: Obstetrics and gynecology (Obstet Gynecol) Vol. 125 Issue 6 Pg. 1487-1489 (Jun 2015) ISSN: 1873-233X [Electronic] United States
• PMID: 25774931 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antidepressive Agents, Tricyclic
• Amitriptyline

Topics

• Adult
• Amitriptyline (therapeutic use)
• Antidepressive Agents, Tricyclic (therapeutic use)
• Female
• Humans
• Pregnancy
• Pregnancy Complications (drug therapy)
• Vomiting (drug therapy)